ARQUÉ Dispensing Nozzles used in 3D Bioprinting Research

Leading experts within the field of regenerative medicine agree that 3D printing technology has limitless potential and a promising roadmap ahead. In the future, it will be possible to 3D print fully functional organs such as livers and kidneys and other body parts like noses, ears and bladders each with our own cells. Tecdia’s technology and innovations are enabling 3D biomaterial printing research.

The Challenge:

Printing Human Organs with High Precision

One method of 3D printing organs is to create supporting structures with polymer biomaterials, layering host cells from the bottom up. Accuracy, temperature and speed are critical for this process.
A high printing resolution of the supporting structure is necessary so complex features of organs can be recreated. The temperature of biomaterials needs to be controlled and maintained and host cells have to be placed quickly to remain protected and promote development and regrowth. Our customers were in search of solutions that enable this technology.

Organ printing process (kidney)

The Solution:

10 Micron Dispensing Nozzles, High Pressure Pump with Suck-back Function and Advanced Heating System

Using precision engineering and machining, Tecdia developed a stainless steel dispensing nozzle with an I.D. of only 10 microns.

ARQUÉ Premium
10µm Nozzle Tip

Attached to the print head, the 10 micron nozzle made it possible to print in high resolution and also gave way to 2 new innovations.

1) High Pressure Pump with Suck-back Function

Tecdia developed a high pressure pump which reduced the printing time by 60% and also eliminates drips and line crossover during printing. This saves time, eliminates waste and reduces cell necrosis.

speed_1

Printing Speed Improvement*

*When printing cubic structure (6x6x2mm)

2) Advanced Heating System

To provide the printing system flexibility with a wide variety of biomaterials, a precision heating system was needed to provide up to 300°C of localized heating. Typical heating systems were limited to only 100°C which reduced biomaterial selection.